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Ciprofloxacin – IV and oral: Dose adjustment for renal impairmentCockcroft-Gault CrCl estimates (using the creatinine clearance calculator) should be used for drug dosing rather than the automated MDRD eGFR produced by the clinical chemistry laboratory available on NOTIS.
As ciprofloxacin can increase selection for C.difficile infection and MRSA colonisation/infection, all patients with previous MRSA/C.difficile require microbiology approval to use ciprofloxacin. Refer to renal pharmacist for advice on dosing in haemodialysis and peritoneal dialysis. Refer to critical care pharmacist for advice on dosing in CVVH.
Page last edited: 16/10/2009 |
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Caution; the antibiotic doses recommended on this website are intended for adult patients with normal renal and liver function unless otherwise stated. Dosing advice for patients with renal impairment is available here. |